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Company

Polytheragene

Pépinière Genopole Entreprises – 4, rue Pierre Fontaine
91058 EVRY Cedex – France
Phone: +33 1 69 47 77 25
Email: herve.cheradame@univ-evry.fr

Hervé CHERADAME: President & CEO
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Polytheragene - Genopole's Company Polytheragene - Genopole's Company

#R&D Services and Products

  • Transfection
  • Gene therapy
  • Biomanufacturing
  • Therapeutic proteins
  • Vaccine

Field of Activity

Manufacture and sale of new high performance transfecting agents for gene therapy, high-throughput screening and biomanufacturing.
Cosmetic and therapeutic molecules from plant biomass.

BACKGROUND
The association of two complementary teams from the MPI/LAMBE laboratories at the University of Évry and the molecular biophysics laboratory at Orléans led to the development of two patented polymer families for nucleic acid transfection.
DESCRIPTION OF THE PRODUCTS / SERVICES / TECHNOLOGY
Two families of synthetic agents have been developed. The first is derived from polyethylenimine and the second is formed by amphiphilic triblock copolymers for in vitro and in vivo applications. These compounds offer better efficacy and lower toxicity than market references.
CUSTOMER REFERENCES / COLLABORATIONS / HIGHLIGHTS
New formulas are currently under development at the MPI lab (UEVE).
Common research with biomanufacturers showed the high performances (high efficacy, low toxicity) of these vectors for biomanufacturing in large volumes (higher than 50L) (GMP quality available).
COLLABORATIONS SOUGHT
We are looking for partnerships and co-development opportunities with biomanufacturers, companies offering high throughput cell screening and biotechnology laboratories developing DNA or RNA vaccines. Companies interested in new molecules of therapeutic or cosmetic interest from plant biomass.

  • Further Information

    Annual turnover: Greater than €100,000
    1 exclusive license from the university of Évry
    2 staff members
    Strengths:
    high performance synthetic vectors.
    Complementary teams in chemistry and biochemistry.
    Innovation assets:
    ability to develop high efficacy transfecting agents for specific applications (stem cells and cell suspension cultures).
    Other facts:
    new formulations for RNA transfer.

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With the support from
Région île de France
Ministère de l'Enseignement supérieur et de la recherche AFM-Téléthon
Communauté d'agglomération Grand Paris Sud
Département de l'Essonne - Terre D'avenirs Ville d'Evry-Courcouronnes 2023 CEA Inserm Centre hospitalier Sud Francilien Université d'Evry - Paris Saclay Université PAris-Saclay SEM Genopole

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