GATEx

GATE^x supports the development of synthetic biology projects towards the industrial demonstrator phase.

GATE^x, which stands for ‘Growth And TEst’, embodies the dual mission of this infrastructure:

• Testing,
• Optimising the scale-up of bioprocesses.

Thanks to the use of cutting-edge equipment, the production environment for micro-organisms, bacteria and yeast, will be improved according to the following process:

Who is GATE^x for?

Managed by the Genopole team, GATE^x is an infrastructure for researchers, start-ups and manufacturers looking to optimise their pre-industrialisation of fermentation and biomanufacturing bioprocesses.

Whether in the bioeconomy, food, cosmetics or healthcare sectors, GATE^x makes the transition from laboratory to pilot production, with capacities of up to 20 litres.

Process – Grade R&D -L1+ Screening and testing Upstream process Downstream process Formulation Filling and finishing

GATE^x‘s main services

1. Scale-up of bioprocesses – From small-scale screening to pilot production (up to 20 L).
2. Process development and optimisation – Refining the fermentation process (strain, medium, substrate), optimising supports and adjusting parameters.
3. High-throughput screening – Use of platforms for parallel testing.
4. Analytical and quality control support – Ensuring the reproducibility and robustness of biomanufacturing.
5. Expertise, consultancy and project engineering – Providing in-depth expertise in biomanufacturing and process scaling.
   

GATE^x, a Genopole’s team at your service

After a confidential initial analysis of your needs, the team will propose a development plan under the operational responsibility of our biomanufacturing engineer.

Do you have a development project you’d like us to take on? Make an appointment with the team

Where to find us?

GATE^x is located at the heart of the Genopole biocluster
Pépinière Genopole Entreprises
4 rue Pierre Fontaine
Evry-Courcouronnes (91)

Contact Us !

For more information on Gate^x, fill in this form :

GATE^x , a member of the Paris Biofonderie network

GATE^x  is fully integrated into the Paris Biofonderie, a biofonderie distributed over 4 sites in the Paris region, made up of five entities: Sorbonne Université, INRAe, Institut Curie, Université Paris Cité and Genopole.

The 4 sites are :

• The DNA and Microbes Biofoundry – This platform specialises in high-throughput DNA assembly and micro-organism engineering, with a particular focus on bacteria, yeast and microalgae.
• Mammalian Biofoundry – This platform is dedicated to the engineering of mammalian cell lines and phenotyping for medical and research purposes.
• Acellular Biofoundry – This platform carries out cell-free experiments and develops software solutions to support all projects.
• GATEx – The pre-industrial Biofoundry, designed to validate the screening of strains (aerobic bacteria and yeasts) and substrates, and to demonstrate the industrial viability of academic projects and start-ups in the bioeconomy and health fields.

As a key interface, joining GATE^x and Genopole means gaining access to a range of connections and pre-contractual agreements with industrial partners for large-scale biomanufacturing.