#HealthTech #Innovative therapies
- Beta-lactam ring
As France's leading biocluster, Genopole is an incubator for cutting-edge projects in biotechnology. Located in the city of Évry, just south of Paris, Genopole provides a unique environment for scientists and entrepreneurs seeking to advance research and innovation.Discover >
Genopole accompanies researchers, postdocs and start-up entrepreneurs through all the phases of their projects to ensure the best possible conditions for business development.Discover >
Every day, at Genopole, researchers, entrepreneurs and students cross paths, share ideas and unite forces in a veritable melting pot for innovation.Discover >
Giving wings to research and empowering employment in our community are cornerstones of Genopole's mission. Catch up on recent scientific advances, the accomplishments of our biotech actors and the events that enliven the biocluster.Discover >
#HealthTech #Innovative therapies
Quibiotic develops three molecular synthesis platforms aimed at innovatively modifying β-lactam rings for new anti-infectives.
The roots of Quibiotic’s technology are to be found in an initial independent patent filed in 2016 by Paolo Bonomi. The base concept of the Quibiotic project is to reconsider lactam rings with the goal of developing novel therapeutics. In 2018, a second Italian patent was filed, in 2019, the project was selected for the Genopole Shaker program and in 2020 a third patent was filed. Thereafter, Quibiotic was officially created on 10 October 2021 by four associates with complementary competencies.
DESCRIPTION OF THE PRODUCTS / SERVICES / TECHNOLOGY
Quibiotic proposes three molecular synthesis platforms for the chemical modification of β-lactam rings in only three to four steps. The company’s technology makes it possible to link any given biologically active molecule to the β-lactam ring. Experimental trials have demonstrated class D β-lactamase inhibition activity for a first molecule and antineoplastic activity for a second one.
ACCOMPLISHMENTS / PARTNERSHIPS / HIGHLIGHTS
A project is currently underway in partnership with the University of Évry-Paris Saclay and Professor N. Jarroux at Lambe to study the complexation of different substrates with cyclodextrins. The goal of this work is to modulate the bioavailability or the activity of our novel compounds.
We are actively seeking project partnerships with public and/or private institutions to empower the development of our platforms and to enable symbiotic relations with other technologies complementary to ours.
Innovation in molecular synthesis strategies. Creation of a library of novel compounds. Simple chemical steps. Expertise in chemistry & biology + complementary competencies among the associates and an advisory board.
A new way of thinking about β-lactam matrices.
Passion, dedication and ethics.
In the same filed
Activity of research, sale, production, distribution and marketing of all unregulated food and agri-food products.Discover
Standing Ovation is developing the production of casein via precision fermentation to enable non-animal-derived cheese and milk substitutes.Discover
STH BIOTECH is developing an innovative cannabis-based process for the reliable and sustainable production of active compounds for the well-being and healthcare sectors.Discover
Synovance has developed a revolutionary synthetic genomics platform for the conception of robust industrial bioproduction strains.Discover
We develop an in vitro manufactured targeted DNA vector to improve the efficiency of therapeutic cell transfection and to reduce the cost of gene-based therapies.Discover
Production as a service (PaaS) platform capable of producing recombinant proteins & enzymes cheaper and on a scale.Discover
Altar is a specialist in the conception and operation of automated fluidic continuous culture systems for adaptive laboratory evolution and the development of microbial strains for industry.Discover
YposKesi is the first French company to develop and manufacture gene and cell therapy products for rare diseases.Discover
WatchFrog markets in vivo biotechnological solutions for environmental risk assessment and the evaluation of the therapeutic, toxic or pollutant potential of all types of chemical, cosmetic or pharmaceutical compounds.Discover
R & D services in the field of transient expression of recombinant proteins in plants.Discover
Pharming specializes in the production of recombinant proteins in transgenic rabbit milk.Discover
Glowee is a cleantech startup developing a disruptive lighting technology based on bioluminescence (the natural light-producing property of certain living organisms).Discover
Global Bioenergies is developing a process to convert renewable resources into hydrocarbons through fermentation.Discover
Abolis develops custom-order microorganisms able to produce molecules of interest via fermentation for the health, nutrition, chemistry and cosmetics sectors.Discover