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PhinC Development


5, Rue Henri Desbruères – Campus 1 – Building 8
91030 EVRY Cedex – FRANCE
Phone: +33 1 76 91 24 66
Email: contact@phinc.fr

Bernard ORLANDINI: CEO, co-founder
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#R&D Services and Products

  • Early drug development (preclinical, I and IIa phases)
  • Modeling & simulation
  • Pharmacometrics
  • Pharmacokinetics-Pharmacodynamics (PK/PD)

Field of Activity


Drug development support to biotech and small pharma companies in early phases from preclinical studies to phase IIa trials.

BACKGROUND
PhinC was founded at the Genopole biocluster in 2008 by four experienced CRO/pharmaceutical professionals with complementary competencies (pharmacology, biostatistics, pharmacokinetics, biomedical R&D).
DESCRIPTION OF THE PRODUCTS / SERVICES / TECHNOLOGY
PhinC uses an integrated and multidisciplinary approach to provide custom-tailored scientific and operational support for companies developing drug candidates. According to your needs, we can provide partial or all-inclusive services in the following fields of activity:

  • Scientific and methodological support: 

By furnishing supplementary expertise, PhinC provides support to the client’s R&D team thus allowing this latter to first conceptualize and then pilot the development of its product.
We provide pertinent counseling for fast decision making and concrete assistance for effective deployment.
Our services include the conceptualization and monitoring of preclinical and clinical trials, the development of rationale for first-in-human trials, assistance for appropriate subcontractor selection (CRO and academic) and the constitution of associated regulatory and scientific dossiers.

  • Pharmacometrics analyses: 

PhinC provides to its clients its multidisciplinary skills in pharmacokinetics (PK), pharmacodynamics (PD), PK/PD, toxicology, physiological based pharmacokinetics (PBPK), PK/QT (cardiac safety), PK population and all related statistical analyses.
Through modeling and simulation techniques, PhinC builds predictive pharmacological models allowing the optimization of drug development plans: MBDD approach (Model-Based Drug Development).

Collaborations sought

Partnership for the implementation of an integrated drug discovery platform to strengthen our drug candidate optimization activity.

  • Further Information

    16 staff members
    Strengths:
    We offer an integrated, custom-tailored approach to optimize early-phase costs and timelines so that our clients can successfully manage their development.
    With our innovative PK/PD, biostatistics and modeling and simulation applications, we can provide support at the earliest research phases to adapt and valorize drug development.

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