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Company

FABMID


4, rue Pierre Fontaine – Genopole Campus 3
91058 EVRY-COURCOURONNES Cedex – FRANCE

Andrey Pichugin: CEO & CSO
Web Site >

Shaker#Industrial Biotech

  • Cell therapy
  • Gene therapy
  • Non-viral vectorBooster
  • Cell transfection
  • CAR-T cells
  • Bioproduction

Field of Activity


We develop an in vitro manufactured targeted DNA vector to improve the efficiency of therapeutic cell transfection and to reduce the cost of gene-based therapies.

BACKGROUND

Fabmid has been incorporated in 2020 with the aim of providing novel skills and experience in the development of cell & gene therapies.
Andrey PICHUGIN (PhD, former leader of a public research lab and Founder of Fabmid SAS) developed a method to produce the first circular vector DNA molecules covalently bound with delivery vehicles of choice that target the vector to cellular nucleus.

DESCRIPTION OF THE PRODUCTS / SERVICES / TECHNOLOGY
Fabmid SAS develops safe and efficient solutions for the growing markets of cell & gene therapies. The company aims to ensure the efficient production of CAR-T-cells for helping millions of patients heal from solid and blood cancers.

Fabmid’s products: (1) circular DNA molecules covalently bound with aptamers for targeted vector delivery into cell nucleus and (2) technological platform for the vector production.

COLLABORATIONS SOUGHT

  • Biopharma developing cell or gene therapy.
  • Academic laboratories and/or biotech companies experimenting in the field of oncology, immunology, cell&gene therapy, virology…

 

  • Further information

    Our competitive advantages:

    • Scalable production on a GMP-compliant technological platform, which belongs to emerging cell-free technologies for the generation of synthetic DNA vectors;
    • Transportation and storage of degradation-resistant vector is compatible with flexible logistics schemes;
    • Highest safety features of the vector include a low error-rate in the DNA sequences, no innate immune response against the vector and prevention of integration into the patient’s genome;
    • Clinical application of the modular “lego-like” vector can be designed for repetitive administrations and persistent transgene expression in dividing cells of patients;
    • Economic models may be implemented at an affordable cost for CAR-T cells treatment of cancers and for other gene therapies.

    2 Patents

    Strengths:
    A cutting-edge technology for numerous applications, a very large market and a complementary team.

    Innovation Assets:
    A robust technology, highly valuable for clinical application and scalable for industrial production.

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