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Laboratory

LaMME – Laboratory Mathematics and Modeling of Evry


Institut de Biologie Génétique et Bio-informatique (IBGBI) – 23, boulevard de France (3e et 4e étage)
91037 EVRY cedex

Director : Stéphane MENOZZI
Web Site (french) >
LaMME - laboratoire génopolitain LaMME - laboratoire génopolitain

#Bioinformatics / Mathematics

  • Bayesian
  • Modeling
  • Statistical analysis
  • Sequence evolution
  • Massive comparison
  • Genetics
  • Dynamic systems
  • Stochastic processes
  • Partial derivative
    equations
  • Financial mathematics

Supervisors:

UEVE - Tutelle laboratoire génopolitainINRACNRS - tutelle de laboratoires génopolitainsensiie - tutelle de laboratoires génopolitains

Field of Activity


Mathematics and applications.

– Développement d’outils mathématiques pour l’analyse de séquences biologiques (chaînes de Markov) et de réseaux génomiques
– Analyse de données d’expression et de SNP
– Statistique des thérapies génique et cellulaire
– Étude des E.D.P. dispersives et des E.D.P. paraboliques
– Bio-mathématique
– Développement de méthodes numériques en analyse et en probabilités

LaMME covers a broad range of research in mathematics and its applications structured across three teams:

  • Analysis and PDE.
  • Probabilities and Financial Mathematics.
  • Statistics and Genomes (S&G).

Particularly, the S&G team focuses its activities on the:

  • conceptualization of statistical methods for the analysis of DNA or protein sequences and for the study of associated molecular expression,
  • and the availability of these methods for the biology community via web-based technologies.

The major research orientations are:

  • statistical inference in genomic networks (interaction, regulation, metabolic pathways), based on data obtained from a range of experimental conditions or on dynamic data;
  • analysis of genome data to identify genes involved in disease causation (analysis of single nucleotide polymorphisms) and the study of gene expression mechanisms over time (Markov models, etc.);
  • study of gene associations, support for automated annotation via massive sequence comparisons;
  • transposable elements;
  • study of the evolution of protein sequences;
  • and the analysis of transcriptome/proteome data.

Detailed descriptions of the two other teams, Analysis and PDE and Probabilities and Financial Mathematics, are provided on the laboratory’s website.

  • COLLABORATION / CHAIR

    COLLABORATIONS

    • Numerous scientific collaborations with laboratories in France and abroad. At Évry:
    • GenHotel,
    • Genoscope,
    • CNRGH.
    • Scientific contracts with industrial partners (Bioptimize, Carpe Aeam, Scor, LCH, Zeliade, Crédit Agricole), most of which appertain to the fulfillment of CIFRE theses.
    • Contract “Big Data for Real-Time Macroeconomics”, involving three companies (Crédit Agricole, Quant Cube, Terra NIS) and three laboratories (SAMOVAR, LAMA, LaMME).

    CHAIR

    Financial mathematics chair “Markets in Mutation”, University of Évry / Ecole Polytechnique / FBF.

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Genopole’s Laboratories

#Bioinformatics / Mathematics


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With the support from
Région île de France