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Company

Pharnext SA

Pépinière Genopole Entreprises
4, rue Pierre Fontaine – Genopole Campus 3
91058 EVRY cedex – FRANCE
Phone: +33 1 60 87 89 48

David HORN SOLOMON: CEO
Web Site >
Pharnext - Genopole's company Pharnext - Genopole's company

#Santé & Bien-être #Therapeutics

  • Genomics
  • Big data
  • Artificial intelligence
  • Network pharmacology
  • Drug repurposing
  • Molecule combinations
  • Biomarkers

Field of Activity

Pharnext develops new therapies and biomarkers based on network pharmacology with a proprietary discovery platform. The company is focused on pathologies with high unmet medical needs. These include neurodegenerative, orphan and common diseases (Charcot-Marie-Tooth disease Type 1A, Alzheimer’s disease, amyotrophic lateral sclerosis (ALS)).

BACKGROUND
Pharnext was founded by renowned scientists and entrepreneurs (including Professor Daniel Cohen, a pioneer in modern genomics) to develop new therapies targeting several key pathological mechanisms in severe orphan and common neurodegenerative diseases.
DESCRIPTION OF THE PRODUCTS / SERVICES / TECHNOLOGY
Pharnext’s approach is applicable to virtually any disorder and particularly suited to multifactorial diseases.
Pharnext is currently focused on neurodegenerative diseases:

  • Charcot-Marie-Tooth (CMT1A) disease: PHASE 3 trial completed – with positive topline results.
  • Alzheimer’s disease: Phase 2a trial completed.
  • ALS: Phase 1 trial completed.

CUSTOMER REFERENCES / COLLABORATIONS / HIGHLIGHTS
€91 million in equity raised from a foundation.

  • Listed on the Euronext Growth trading market in July 2016.
  • CMT1A program completed phase 3 trials with positive topline results.

COLLABORATIONS SOUGHT

  • Industrial partnerships in the pharmaceutical sector for Pharnext’s candidate drugs.
  • R&D collaborations with academic and industrial partners for early programs.
  • Further Information

    60 patent families
    45 staff members
    Strengths:
    New paradigm in R&D for faster pharmaceutical developments, particularly in multifactorial diseases. Eminent scientists and breakthrough approaches in pharmacogenomics.
    Innovation assets:
    Innovative drug combinations based on genomic big data and artificial intelligence. Pharnext’s approach can potentially be applied to any disease.

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With the support from
Région île de France
Ministère de l'Enseignement supérieur et de la recherche AFM-Téléthon
Communauté d'agglomération Grand Paris Sud
Département de l'Essonne - Terre D'avenirs Ville d'Evry-Courcouronnes CEA Inserm Centre hospitalier Sud Francilien Université d'Evry - Paris Saclay Université PAris-Saclay SEM Genopole

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